Paraquat (۱,۱-dimethyl-۴,۴-dipyridinium chloride), also known as methyl viologen, is one of the most widely used herbicides of toxicological class I in about ۱۳۰ countries [۱]. It is consideres as an effective herbicide in spite of its highly toxicity for humans and animals [۲].In the present study, a simple synthesis approach was applied to prepare the core-shell Fe۳O۴@SiO۲@SBA۳-SO۳H mesoporous magnetic nanoparticles (MMNPs-SO۳H) as an effective۲sorbent for paraquat removal from the aqueous solutions. The characterization of MMNPs-SO۳H was done by XRD, BET, BJH, FT-IR, FE-SEM, VSM, EDX and TEM instruments. The effect of the influential experimental variables including solution pH, adsorbent amount, contact time and ionic strength at four levels were optimized in ۵۰ mL solution containing ۲۵ mg L-۱ paraquat by Taguchi design method (OA۱۶). Based on the ANOVA results, ionic strength (۸۰.۶۹ %) recognized as the most important factor contributing to the removal efficiency of paraquat followed by adsorbent mass (۱۲.۶۷%), pH of solution (۳.۵۲%) and stirring time (۰.۱۴۱%). The replicate removal experiments at optimum conditions (sample volume = ۵۰ mL, adsorbent dosage = ۰.۱۲ g, solution pH = ۷, ionic strength = without salt addition, contact time = ۳۰ min) confirmed good removal efficiency as ۸۶.۹ %. The four kinetic models for the paraquat adsorption on the MMNPs-SO۳H were investgated and according to the obtained results, the pseudo-second order kinetic model was known as the best kinetic model (R۲ > ۰.۹۹, qe,cal =۸۰.۰ mg g-۱) showing the diffusion appears to play a key role in determining rate of adsorption onto the porous adsorbent. Adsorption equilibrium data were investigated by Langmuir, Freundlich, Temkin, and Dubinin‐Radushkevich isotherm models for explanation the adsorption systems at equilibrium. Thermodynamic study showed the temperature effects on the paraquat adsorption to obtain the thermodynamic parameters. The negative ΔH° and ΔG° values indicated the exothermic and spontaneous nature of paraquat sorption on the surface of MMNPs-SO۳H. The negative ΔS° shows a decrease in the randomness at the interface of solution-adsorbent with the progress of sorption process. The negative Ea confirmed the physisorption process by exothermic nature of adsorption process.Finally, tha applicability of the proposed adsorbent for adsorption of paraquat from real aqueous samples were investigated and satisfactory results were obtained.