Synthesis of ۱,۸-dioxo-octahydroxanthenes under solvent-freeconditions via Phosphorus pentoxide supported on alumina(P۲O۵/Al۲O۳) catalyzed tandem reaction of Aldehyde withdimedone

Phosphorus pentoxide used on alumina (P۲O۵/Al۲O۳) as an inexpensive, eco-friendly andnon-toxic acid catalyst for the one-pot synthesis of ۱,۸-dioxo-octahydroxanthenes via multicomponentreactions under solvent-free conditions. The present approach offers severaladvantages such as short reaction times, high yields, easy purification, recovery andreusability of the catalyst.

Keywords:

۱ , ۸-Dioxo-octahydroxanthenes , Solvent-free , Multicomponent reactions , Phosphorus pentoxide used on alumina