Synthesis of Pyridopyrimidine-Indole Hybrids Using γ-Fe۲O۳@HAp@PBABMD@Cu as Efficient Magnetic Nanocatalyst

A novel and practical method for the synthesis of pyridopyrimidine-indole hybrids, using a three-component reaction of thiouracil or ۶-amino-N,N-dimethyluracil, various aryl aldehydes and ۳-cyanoacetyl indole in the presence of a green heterogeneous nano-catalyst γ-Fe۲O۳@HAp@PBABMD@Cu was developed. This protocol furnished the desired products in high yields (۸۲-۹۵%) and lower reaction times (۱۸-۴۰ min).

Keywords:

Pyridopyrimidine , ۳-Cyanoacetylindole , ۶-Amino-N , N-dimethyluracil , Aanocatalyst , γ-Fe۲O۳@HAp@PBABMD@Cu

Authors

Nesa Haghgoo

Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box ۴۱۳۳۵-۱۹۱۴, Rasht, Iran

Manouchehr Mamaghani

Department of Chemistry, Faculty of Sciences, University of Guilan, P. O. Box: ۴۱۳۳۵-۱۹۱۴, Rasht, Iran

Elham Saberikhah

Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box ۴۱۳۳۵-۱۹۱۴, Rasht, Iran

Roghayeh Hossein Nia

Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box ۴۱۳۳۵-۱۹۱۴, Rasht, Iran

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https://civilica.com/doc/1766085

شناسه ملی سند علمی:

JR_ORGC-7-2_006

تاریخ نمایه سازی: 3 مهر 1402

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Haghgoo, Nesa and Mamaghani, Manouchehr and Saberikhah, Elham and Hossein Nia, Roghayeh,1400,Synthesis of Pyridopyrimidine-Indole Hybrids Using γ-Fe۲O۳@HAp@PBABMD@Cu as Efficient Magnetic Nanocatalyst,https://civilica.com/doc/1766085

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Type of center: دانشگاه دولتی

Paper count: 20,214

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