Design, Characterization and Application of SO۳H-Functionalized Phthalimide as a Highly Efficient Catalyst for the Condensation of Dimedone with Arylaldehydes, β-Ketoesters and Ammonium Acetate

In this work, SO۳H-functionalizedphthalimide (SFP) as a SO۳H-containing solid acid is prepared by the reaction of phthalimide with chlorosulfonic acid, and characterized by FT-IR, ۱H and ۱۳C NMR, Mass, TG, DTG, XRD and SEM. Then, it is utilized as a highly efficient, heterogeneous and green catalyst for the one-pot multi-component condensation of dimedone with arylaldehydes, β-ketoesters and ammonium acetate under solvent-free conditions to afford polyhydroquinolines in excellent yields and in short reaction times.

Keywords:

SO۳H-functionalized phthalimide (SFP) , SO۳H-containing solid acid , Dimedone , Arylaldehyde , β-Ketoester , Polyhydroquinoline