HHb-binding and Anticancer Activities of Green Synthesized ZnO Nanoparticles

In this investigation, the interaction of the green synthesized zinc oxide nanoparticles (ZnO NPs) through Echinophora platyloba DC. (E. platyloba) extract mediated synthesis with Human hemoglobin (HHb) was investigated employing different spectroscopic methods. The results of the MTT assay exhibited that green synthesized ZnO NPs have efficient anticancer potential on Raji cell line. The results of CD spectrometry showed that the secondary structure of HHb remains unchanged, suggesting that the green synthesized ZnO NPs could be employed as a carrier in the drug delivery system without any cytotoxicity effect.

Keywords:

ZnO NPs , Green chemistry , Extract , HHb , Anticancer