Antibacterial, Antifungal activity of simple and mixed ligand Fe(III),Cr(III) complexes

The Schiff base, Schiff base complexes and Schiff base mixed ligand complexes were screened for antibacterial and antifungal activities. It is observed that Schiff base mixed ligand complexes has the good antibacterial and antifungal activities. This result supported by the docking analysis it reveals that the [Cr(SBL۱)۲ Cl۲]Cl, [Fe(SBL۱)(PPh۳)۲Cl۲]Cl, and [Fe(SBL۴) (PPh۳)۲Cl۲]Cl form bonded and non-bonded interactions with the N-myristoyltransferase receptors.

Keywords:

Schiff base Fe (III) and Cr (III) complexes , antibacterial , Antifungal activity , molecular docking studies