Comparison of the Unstimulated whole Saliva Flow Rate in Diabetic Type II Patients with Healthy Individuals

Objective: Diabetes Mellitus is one of the most common metabolic disorders which have several oral complications such as hypofunction of salivary glands. The aim of present study was to compare the unstimulated whole saliva (UWS) flow rate in diabetic type II patients and healthy peoples who admitted in Yazd Diabetic center. Materials and Methods: In this analytic-observational study, ۷۸ patients with diabetic type II and ۷۴ healthy people were selected. At first the xerostomia was checked and then the UWS flow rate was measured by spitting method. Data were analyzed by ANOVA, Chi-square and Multiple way variance tests using SPSS software version ۱۱. Results: the participants were between ۳۰-۶۹ years old including ۱۰۳ female (diabetic (۵۳), healthy (۵۰)) and ۴۹ male (diabetic (۲۵), healthy (۲۴)) were selected. The mean of UWS flow rate in diabetic patients was (۰.۰۷±۰.۰۳ ml/min) which was statistically less than healthy people (۰.۱۳±۰.۰۳۶ ml/min) (P< ۰.۰۰۲).The mean of UWS flow rate in relation to age was significantly different and adverse relationship between UWS flow rate and FBS was found in diabetic type ۲ patients (P<۰.۰۰۰, r=-۰.۳۸۹). Also diabetic patients complain about xerstomia more than healthy people significantly (۸۳% versus ۲۸.۴%, P< ۰.۰۰۱). Conclusion: The complaint of xerstomia and decrease of UWS flow rate was more common in diabetic patients than healthy people also good FBS control can prevent xerostomia.

Keywords:

Xerostomia , Unstimulated whole saliva , Diabetes mellitus Type ۲.