Clinical characteristics and outcomes of COVID-۱۹ patients with a history of cardiovascular disease
Publish place: Journal of Current Biomedical Reports، Vol: 3، Issue: 1
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JCBIOR-3-1_006
تاریخ نمایه سازی: 14 آذر 1402
Abstract:
New emerging severe acute respiratory syndrome coronavirus-۲ (SARS-CoV-۲) primarily affects the lungs, but the virus may cause cardiovascular disease (CVD), and a history of CVD is usually associated with comorbidities, which could increase the severity of infections. In this study, we collected demographic and clinical characteristics data from ۱۲۳ patients with a history of CVD, who were confirmed to have SARS-CoV-۲ infection by polymerase chain reaction (PCR) test in Razi Hospital, Rasht, Iran, from March ۲۰۲۱ to June ۲۰۲۱. Chi-Square and Fisher's Exact test with a significance level of P less than ۰.۰۵ was performed. All statistical analysis was performed with SPSS software version ۲۶.۰. Among the studied patients, ۹۹ patients were discharged and ۲۴ of them died. ۶۲ (۵۰.۴%) of the study population were female and ۶۱ (۴۹.۶%) were male, and there is no significant association between gender and the outcome of patients (P = ۰.۱۵۹). The total mean age of patients was ۶۸.۳۵±۱۲.۴۱. Statistical analysis has represented a significant relation of death outcomes in CVD patients with age ۶۰ years and older (P = ۰.۰۰۱), in comparison with patients younger than ۶۰ years. In this present study, no significant relation between underlying disease and mortality rate was reported, but in COVID-۱۹ patients with a history of CVD and age upper than ۶۰ years, death outcome was more probable.
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Authors
Tofigh Yaghubi
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Vahid Shakoori
Department of Cardiology, Guilan Interventional Cardiovascular Research Center, Heshmat Hospital, Guilan University of Medical Sciences, Rasht, Iran
Sara Nasiri
Department of Cardiology, Guilan Interventional Cardiovascular Research Center, Heshmat Hospital, Guilan University of Medical Sciences, Rasht, Iran
Mona Keivan
Student Research Committee, Medical School, Kermanshah University of Medical Science, Kermanshah, Iran