Ultrasound-guided (USG) transversus abdominis plane (TAP) block with bupivacaine and dexmedetomidine on the control in postoperative analgesia of inguinal hernia surgery: A randomized clinical trial
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JCOMS-3-2_007
تاریخ نمایه سازی: 14 آذر 1402
Abstract:
Introduction: Transversus abdominis plane block (TAPB) is now a well established technique in postoperative
analgesia for lower abdominal surgeries. We aimed to investigate the effects of adding dexmedetomidine to bupivacaine
used in USG (TAP block on postoperative pain and complications in patients undergoing inguinal hernia repair repair.
Materials and Methods: About ۶۶ eligible patients enrolled in the survey. They were randomly assigned to one of the
two groups of ۲۰ CC of bupivacaine ۰.۵% + ۱ CC Normal saline or ۲۰ CC of bupivacaine ۰.۵% + ۱۰۰µg
dexmedetomidine. The amount of pethidine consumption, postoperative VAS score, and complications were measured.
Patients were evaluated at the recovery ward (T۰) and ۲, ۴, ۶, ۱۲, and ۲۴ hours after surgery. Regarding the VAS score
and if the patient's pain complained from a VAS≥۳, pethidine ۰.۵ mg/kg was administered. The total dose, the average
dose of pethidine used, and the first time of pethidine administration after the nerve block was recorded
Results: Two groups had no significant diff erence regarding baseline characteristics. A significant difference was
found at T۴ about VAS (P=۰.۰۰۵). The amount of pethidine consumption was lower in the DEX group but not
statistically significant except for T۴ (P=۰.۰۰۶). The two groups showed no diff erence regarding side effects such as
PONV
Conclusion: Injection of dexmedetomidine in combination with bupivacaine for TAPB is an effective and safe drug
for controlling pain after hernia surgery.
Keywords:
Authors
Hossein Khoshrang
Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
Hossein Hemmati
Department of Vascular Surgery, Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Mohammad Reza Habibi
Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
Mohaya Farzin
Department of physiology, Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran