Establishment of Reference Intervals for Renal Function Clinical Chemistry Parameters in an Indonesian Tertiary Hospital
Publish place: Archives of Razi Institute journal، Vol: 78، Issue: 3
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
View: 59
This Paper With 7 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ARCHRAZI-78-3_020
تاریخ نمایه سازی: 6 دی 1402
Abstract:
Reference intervals aid clinical decision-making for clinical chemistry values. Laboratory test results are compared to reference intervals to aid in the diagnosis, therapy, and monitoring decisions. Due to the differences in ethnicity, gender, age, and analytical methods, reference intervals (RIs) vary between populations. This study aimed to establish the reference values for renal function tests in targeted populations in Indonesia. This research was conducted with a cross-sectional observational analytic design. The research sample consisted of medical check-up data from health professionals at Dr. Mohammad Hoesin Hospital in Palembang, Indonesia. The Kolmogorov-Smirnov test was used to determine the normality of data distribution. The RIs were computed using reference limits at the ۲.۵th and ۹۷.۵th percentiles (abnormal distribution) or ±two standard deviations (±۲ SD) (normal distribution). The independent t-test (parametric) or Mann-Whitney test was used to compare the RIs of males and females (non-parametric). Males and females had a significant difference (P<۰.۰۰۱) regarding the values of uric acid, urea, and creatinine parameters, requiring the reference intervals to be separated. The following reference intervals were established: uric acid: ۲۳۰,۷۸-۵۲۶,۹۹ mol/L for males and ۱۷۹,۰۳-۴۱۵.۱۷ mol/L for females, urea: ۲,۲۲-۴,۹۹ mmol/L for males and ۱,۷۸-۴,۲۸ mmol/L for females, and creatinine: ۶۱,۰۱-۱۰۶,۹۹ mol/L for males and ۴۰,۶۷-۷۷,۸۱ mol/L for females. This study defined gender-specific RIs for three renal function test parameters for the adult population of Palembang, Indonesia. The deployment of population-specific RIs may facilitate better laboratory testing.
Keywords:
Authors
P Liana
Department of Clinical Pathology, Faculty of Medicine, Universitas Sriwijaya, Mohammad Hoesin General Hospital, Palembang, Indonesia
O Olivia
Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
S Fertilita
Department of Histology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
T. P Umar
Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :