Evaluation of Therapeutic Properties of a Low Energy Electron Beam Plus Spoiler for Local Treatment of Mycosis Fungoides: A Monte Carlo Study

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JBPE-10-4_006

تاریخ نمایه سازی: 30 دی 1402

Abstract:

Background: When using low-energy electron beams for the treatment of skin lesions, such as Mycosis Fungoides (MF), a beam spoiler is used to decrease electron therapeutic depth (R۹۰) while increasing the surface dose.Objective: The aim of this study was to evaluate the characteristics of a ۵ MeV electron beam when using a spoiler for the local treatment of MF skin lesions by Monte Carlo (MC) simulation.Material and Methods: In this experimental study, a Siemens Primus treatment head and an acrylic spoiler, positioned at the end of applicator, were simulated using BEAMnrc, an EGSnrc user code. The modelled beam was validated by measurement using MP۳-M water tank, Roos parallel plate chamber and Semi flex Chamber-۳۱۰۱۳ (all from PTW, Freiburg, Germany). For different spoiler thicknesses, dose distributions in water were calculated for ۲ field sizes and were compared to those for the corresponding open fields.Results: For a ۱.۳ cm spoiler, therapeutic range changed from ۱.۵ cm (open field) to ۰.۵ cm and ۰.۴ cm for ۱۰ × ۱۰ cm۲ and ۲۰ × ۲۰ cm۲ field sizes, respectively. Maximum increase in penumbra width was ۲.۸ and ۳.۸ cm for ۱۰ × ۱۰ cm۲ and ۲۰ × ۲۰ cm۲ field sizes, respectively. Maximum increase in bremsstrahlung contamination was %۲ in both field sizes.Conclusion: R۹۰ decreased exponentially with increase in spoiler thickness. The effect of field size on penumbra was much larger for spoiled beam compared to the open beam. The results of this research can be applied to optimize the radiation treatment of MF patients in our hospital.

Authors

S Noshadi

MSc, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

M Atarod

PhD, Department of Medical Physics and Radiology, Shahrekord University of Medical Sciences, Shahrekord, Iran

A Amouheidari

MD, Department of Radiation Oncology, Milad Hospital, Isfahan, Iran

F Felfeliyan

MSc, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

P Shokrani

PhD, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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