Relative Frequency of Rotavirus Gastroenteritis in Children below ۳ Years Old with Acute Gastroenteritis Referred to Afzalipour Hospital in Autumn ۲۰۰۸

Background & Aims: Diarrheal diseases are one of the major causes of morbidity and mortality in infants and toddlers in developing countries and Rotavirus is the single most important cause of severe infantile gastroenteritis worldwide. This study was conducted to estimate the frequency and clinical manifestations of rotavirus infection in children below ۳ years old with acute gastroenteritis referred to Kerman Afzalipour Hospital in autumn ۲۰۰۸ in order to emphasize on infants’ vaccination against rotavirus. Methods: In this study, ۱۱۸ stool specimens were examined with Gel Electrophoresis for rotavirus. Children less than ۳ years old who had gastroenteritis with duration of less than ۲ weeks were included into the study. Results: From ۱۱۸ stool specimens, ۲۴.۶% (n=۲۹) were positive for rotavirus. Mean age of children with rotavirus gastroenteritis was ۱۴.۴ months. Fifty percent of rotavirus infected children were male and ۵۰% were female. Clinical manifestations of rotavirus infections were fever (۶۵/۵%), vomiting (۶۵.۵%), rinorrhea (۲۴.۱%), mild dehydration (۴۶.۴%), moderate dehydration (۳۵.۷%) and serve dehydration (۱۷.۹%). From all, ۵۱.۷% of children with rotavirus gastroenteritis were discharged, ۱۷.۳% were admitted in the Emergency room and ۳۱% were hospitalized in the pediatric ward. Conclusion: Rotavirus is a major cause of acute dehydrating gastroenteritis in children in our region. A considerable percent of these children need primary care, visit in emergency room and admission in pediatric ward. Therefore, further studies to pursue the cost effectiveness of rotavirus vaccine comparing to direct and indirect expenses caused by rotavirus gastroenteritis seems to be necessary.

Keywords:

Rotavirus , Gel Electrophoresis , Gastroenteritis , children