Determining the Frequency of Antibiotic Sensitivity in Blood Infections inn Ardabil province in ۲۰۱۰-۲۰۱۱

Determination of the frequency of bacteria isolated from blood culture and the pattern of their antibiotic sensitivity is epidemiologically of great importance and can help choosing primary antimicrobial treatment. The aim of the current study was to determine the most common bacterial factors of blood infection and their antibiotic sensitivity in a one year period from October ۲۰۱۰ till the end of September ۲۰۱۱ in Imam Khumeini hospital of Ardebil. Data collected from total of ۱۴۶۹ patients susceptible to blood infection hospitalized in Imam Khumeini hospital and analyzed using SPSS (version ۱۸) statistical software and investigated with descriptive statistics and frequency diagrams. Only values with P≤۰.۰۵ were considered as significant. The highest rate of bacteremia prevalence observed in emergency unit. Of ۱۴۶۹ blood sample, ۹۱ (۶.۱۹%) were infected with bacteria. Infection prevalence reported higher in male (۵۵.۴%) than to female (۴۴.۶%). The most common bacteria isolated were, Negative-coagulase Staphylococcus (۳۷.۳%), Escherichia coli (۲۲%), Staphylococcus aureus (۱۱%) and Staphylococcus epidermidis (۱۱%), respectively. The highest antibiotic sensitivity was associated with Gentamicin with the frequency rate of ۴۲ (۵۱.۳%) and Ciprofloxacin with the frequency rate of ۳۵ (۴۲.۷%). Gentamicin and Ciprofloxacin determined as two completely effective antibiotics on isolated strains. Regarding the increased prevalence of infection with Negative-coagulase Staphylococcus in the current study and other similar studies, the morbidity and mortality rate of the disease can be decreased using proper antibiotic treatments complying with the exact results of the disc diffusion test method.

Keywords:

antibiotic sensitivity , Blood infections , Ardabil