Sepsis Diagnosis and Treatment

Publish Year: 1402
نوع سند: مقاله کنفرانسی
زبان: Persian
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شناسه ملی سند علمی:

MSHCONG06_016

تاریخ نمایه سازی: 15 فروردین 1403

Abstract:

Sepsis occurs when a pre-existing infection in the body causes an overreaction of the immune system. When you experience an infection, your immune system reacts by releasing proteins and other chemicals to fight it. Sepsis occurs when this reaction gets out of control and leads to widespread inflammation in the body. Severe sepsis can lead to septic shock, which is an emergency. Septic shock is accompanied by a severe drop in blood pressure, organ failure, and widespread tissue damage. For the treatment of sepsis patients, rapid diagnosis and the initiation of standard treatment are recommended. The treatment of critically ill intensive care patients requires daily re-evaluation. Wiki is one of the important factors in the treatment of microbial dosage adjustments. Mitochondrial dysfunction causes multiple organ failures. Early diagnosis of sepsis and giving antibiotics within ۱ hour after sepsis is suspected are recommended. Sepsis can cause dysfunction of the heart, which is usually called cardiomyopathy. Also, during sepsis, the glycocalyx breaks down, and albumin restores and gradually improves its functions. The endothelium is also a key active factor in sepsis and is the main target for treatment. In fact, during sepsis, endothelial cells strengthen the immune response and regulate the coagulation system. Phagocytosis also removes the pathogen and is a key factor in its resolution. Also, reversing the immunosuppression caused by sepsis by inhibiting the PD-L/PD-۱ pathway is a promising therapeutic approach. In this article, we examine the ways in which we have treated sepsis.

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Authors

parisa sepahvand

MSc in Pathogenic Microbes, Azad University, Khorramabad Branch, Lorestan, Iran