A Regioselective, One-Pot, Ultrasound Assisted, Biginelli-Type Reaction of Aldehyde,Urea/Thiourea and Phenylacetone
Publish Year: 1402
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
OGPCONF09_125
تاریخ نمایه سازی: 19 فروردین 1403
Abstract:
A facile one-pot regioselective and rapid synthesis of various novel ۳,۴-dihydropyrimidin-۲(۱H)-one(DHPMs) via a three-component Biginelli-type condensation of aldehyde, phenylacetone and urea/thiourea under ultrasonic irradiation with good yields is described. Simple and readily available starting materials, mild base-catalyzed reaction conditions, nocolumn chromatography, good to high yields, applying the sonochemical methodology as an efficient method and short reaction times are important features of this protocol.
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Authors
Sayedeh Manijeh Nematpour Turky
Department of Chemistry Education, Farhangian University, Tehran, Iran.