Anaesthetic Effect of Propofol on Rainbow Trout (Oncorhynchus Mykiss) in Two Different Concentrations

Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJVS-12-1_003

تاریخ نمایه سازی: 8 خرداد 1403

Abstract:

Objective- The study aims to determine efficacy of propofol as an inmersión agent to induce anesthesia in rainbow trout (Oncorhynchus mykiss).Design- Experimental study.Animals- ۳۶ healthy rainbow troutProcedure- Trouts were sorted ramdomly in two groups, ۱۸ fish each one. Both groups were anesthesized by bath, one of them with ۲,۵ mg/l, the other one at ۵ mg/l concentration. During the experiment, basal respiratory rate, partial and total equilibrium loss, time to anesthesia, anaesthesia respiratory rate and manipulation response were recorded.Results and Conclusion- Induction and recovery times as well as behavioural response were recorded, being significantly affected by propofol concentration (P <۰.۰۱). After exposure to ۲,۵ and ۵ mg/l, fishes reached stage ۳ anaesthesia in ۴,۹۹ ± ۱,۰۷ and ۲,۸۱ ± ۰,۷۱ minutes respectively. Recovery time were ۳,۵۹ ± ۱,۴۴ for ۲,۵ mg/l and ۷,۴۹ ± ۳,۰۲ minutes for ۵ mg/l. After the experiment, the fish remained for ۴۸ hours in a pond attached to the unit, without any death. This study, showed the behavioural response of rainbow trout to anaesthesia as well effectiveness of propofol as anaesthetic. Propofol induce safe dose dependent anaesthesia, being useful for different tasks related to the management of culture trout, as it meets the criteria established in aquaculture use.Clinical relevance- The results of the present work provide data to be used in surgical procedures and containment maneuvers in the different practices performed in fish farming.

Authors

Guillermo F. Prieto

Department of Pharmacology, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

Natalia F. Urzua

Department of Pharmacology, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

Miguel A. Mancini

Department of Aquaculture, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

Maria P.Tonini

Department of Pharmacology, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

Jimena Messina

Department of Pharmacology, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

Sergio Salas

Boca de Río Fish Farm , Córdoba, República Argentina

Carlos A. Errecalde

Department of Pharmacology, Faculty of Agronomy and Veterinary Medicine, Río Cuarto National University, Río Cuarto, Córdoba, República Argentina

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