Histomorphological Evaluation of Transcutaneous Electrical Neural Stimulation in Healing of Experimentally Induced Partial Hip Joint Cartilage Defect in Rabbit

Publish Year: 1386
نوع سند: مقاله ژورنالی
زبان: English
View: 40

This Paper With 7 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_IJVS-2-5_007

تاریخ نمایه سازی: 8 خرداد 1403

Abstract:

Objective- To determine the effect of the transcutaneous electrical neural stimulation on healing of hip joint cartilage defect in rabbit. Design- Experimental in vivo study. Animals- ۱۲ adult New Zealand rabbits were used. Procedures- Under effective the right femoral head was subluxated and the maximum accessible cartilage was denuded up to subchondral bone using dental bit in each rabbit. Then rabbits were divided into two groups of control( I ) with no treatment and treatment group( II) which were subjected to Transcutaneous Electrical Neural Stimulation on ۳rd day with frequency of ۱۰۰ Hz and ۸۰ ?s intensity daily for ۱۰ minutes in ۱۴ days, having ۶ rabbits each. These groups further were subdivided into ۲ subgroups of ۳ rabbits each with duration of one, and three months. The samples were collected for histomorphological study on day ۳۰ and ۹۰ days which were stained with H&E stain. Results- The samples did not show any local reaction on denuded surface in control group; whereas, the fibrous tissue in the central defect, with progression of the healing tissue to fibrocartilage as healing progressed up to ۳ months in treated ones. Preliminary results indicate an increased stimulation of the repair tissue, as evidenced by total healing of three of the experimental defects with fibrocartilage as compared to the control specimens. Conclusion and Clinical Relevance- TENS as a physical method of therapy is quite effective in cartilage healing and induces faster remodeling of fibrocartilage fibers.