Local discontinuous Galerkin method for the numerical solution of fractional compartmental model with application in pharmacokinetics

This paper provides a numerical solution for the fractional multi-compartmental models which are applied in pharmacokinetics. We implement the local discontinuous Galerkin method for these fractional models with the upwind numerical fluxes. To obtain high-order results with adequate accuracy, the third-order approximation polynomials are used. Finally, to validate the scheme, the results are compared with the solutions of a semi-analytical method.

Keywords:

Local discontinuous Galerkin method , Fractional compartmental model , Pharmacokinetics