Occurrence of ESKAPE Blood Culture Pathogens Isolated in the Intensive Care Units of a Tertiary Care Teaching Hospital in Delhi: A Descriptive Cross-Sectional Analysis

Background: A comprehensive overview of ESKAPE pathogens, highlighting their antibiotic resistance mechanisms and the urgent need to address the clinical impact of these pathogens in bloodstream infections. Objectives: The aim of the present study was to observe the prevalence and trends of antibiotic susceptibility profiles of ESKAPE blood pathogens in Intensive Care Units (ICUs), providing valuable insights for improving patient care and infection control. Methods: A detailed description of our descriptive cross-sectional study conducted in various ICUs, including blood sample collection, antibiotic susceptibility testing, and data management and statistical analysis. Results: The findings of the present study reveal insight into the distribution of ESKAPE pathogens in different ICUs, with a focus on prevalence, age-specific variations, and antibiotic resistance patterns. Conclusion: A thorough discussion on the clinical implications of our results, emphasizing the high prevalence of Acinetobacter baumannii, Staphylococcus aureus, and Klebsiella pneumoniae, and the concerning levels of antibiotic resistance observed.

Keywords:

Pathogen , Antibiotic Resistance , Intensive Care Units , Bloodstream Infections , Surveillance