Efficient and Cost-Effective Fabrication of PMMA Micropores for Resistive Pulse Sensing
Publish place: The 32nd annual international conference of the Iranian Society of Mechanical Engineers
Publish Year: 1403
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ISME32_306
تاریخ نمایه سازی: 15 تیر 1403
Abstract:
This paper delves into the optimization of Poly(methyl methacrylate) (PMMA) micropore size using a comprehensive experimental approach. It begins by highlighting the advantages of PMMA, introducing the concept of drilling a microscale pore in PMMA, and subsequently reducing its size through the application of pressure and heat. The primary goal is to comprehend the influence of pressure, heat, and time on pore dynamics and size alteration. Employing the Taguchi Design of Experiments (DOE), the study systematically investigates the impact of these factors by subjecting a primary ۵۰۰μm pore to variations in pressure, heat, and time. The results demonstrate the substantial impact of temperature on pore size reduction at higher temperatures, with pressure exhibiting a significant effect up to ۱ bar, diminishing thereafter, and time gradually decreasing over the experimental duration. Further exploration focuses on achieving the smallest possible pore size using a ۲۰۰μm drilled micropore, refining it to below ۲۰μm. Ultimately, the micro-sized pore is utilized in a resistive pulse sensing (RPS) setup, revealing resistance variations associated with different pore sizes. This promising technique holds potential for future applications in RPS setups, facilitating the enhanced analysis and detection of proteins or other minute particles.
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Authors
Parham Rahimi
MSc Student, Department of Mechanical Engineering, Sharif University of Technology, Tehran
Maryam Najjar
MSc Student, Department of Mechanical Engineering, Sharif University of Technology, Tehran
Mojtaba Taghipoor
Assistant Professor, Department of Mechanical Engineering, Sharif University of Technology, Tehran