Salivary Secretory Carcinoma in a Patient with Immature Ovary Teratoma
Publish place: Iranian Journal of Otorhinolaryngology، Vol: 36، Issue: 4
Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJOTO-36-4_008
تاریخ نمایه سازی: 17 تیر 1403
Abstract:
Introduction:Secretory carcinoma, previously known as mammary analog secretory carcinoma, is a rare malignancy of salivary glands. It has a diversity of microscopic patterns and is similar to other salivary gland tumors. Case Report:This report presents the case of a ۳۲-year-old female patient with a painless swelling of the upper lip and a history of recent surgery for an immature ovarian teratoma. The microscopic sections revealed a circumscribed neoplasm composed of macrocystic, papillary-cystic, and microcystic patterns with bland vesicular nuclei and vacuolated cytoplasm. Tumoral cells were strongly positive for mammaglobin, SOX۱۰, GATA۳, S-۱۰۰, and vimentin. The diagnosis of salivary gland secretory carcinoma was made. After ۲۲ months, there has been no recurrence. Conclusions:As secretory carcinoma is a relatively new entity, it is necessary to understand its characteristics. Although the overall incidence of second primary cancer in patients with salivary gland cancers is low, the possibility of its presence in such patients should be considered.
Keywords:
Mammary Analogue Secretory Carcinoma , Lip , oral cavity , Salivary gland carcinomas , Secretory carcinoma
Authors
Saede Atarbashi-Moghadam
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali Lotfi
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Sepehr Mirebeigi
Research Committee, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shaghayegh Dowdani
Graduated Student, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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