The Relatıonshıp between Infertılıty and Sleep Qualıty ın Women: Systematıc Revıew and Meta-Analysıs

Objectives: This systematic review and meta-analysis study aimed to examine the relationship between infertility and sleep quality in women. Methods: The literature search was conducted between October and November ۲۰۲۲ with full-text studies from PubMed (MEDLINE), Cochrane, Google Scholar, and Scientific Information Database (SID). The study is based on the recommendations of the Cochrane guidelines. The data were analyzed using the Review Manager computer software (Version ۵.۳). Results: A systematic literature review was conducted, with ۱۱ studies included. The meta-analysis revealed a significant difference between infertility and sleep quality in women, that the sleep quality of infertile patients decreased (SMD: -۰.۷۵ ۹۵% CI: -۰.۸۴ to -۰.۶۶, Z = ۱۶.۴۶, p<۰.۰۰۰۰۱), and that there was a significant difference between infertility and depression (SMD: -۰.۱۸ ۹۵% CI: -۰.۲۷ to -۰.۰۹, Z = ۴.۰۰, p< ۰.۰۰۰۱). Conclusion: The results of this study indicate that sleep quality is low in infertile women.

Keywords:

Women , sleep , infertility , In Vitro Fertilization (IVF) , depression