Synthesis of Functionalized Benzothiadiazine ۱, ۱-Dioxide Derivatives viaIntramolecular C-H Activation Reactions of Benzenesulfonylchloride and N,N′,N′′-Trisubstituted Guanidines

A simple and appropriate procedure for the synthesis of functionalized benzothiadiazine ۱, ۱-dioxide with goodyields via the Cu-catalyzed intramolecular C-H activation reaction from benzenesulfonylchloride and N, N′, N′′-trisubstituted guanidines, generated by copper(II) oxide-catalyzed hydroamination of carbodiimides, is reported.

Keywords:

Copper-catalyzed , C-H Activation , Benzothiadiazine ۱ , ۱-dioxide , N , N'-Dicyclohexylcarbodiimide , Primaryamine , Benzenesulfonylchloride