Maternal Separation and the Risk of Drug Abuse in Later Life
Publish place: Addiction and Health، Vol: 8، Issue: 2
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_AHJK-8-2_002
تاریخ نمایه سازی: 12 مرداد 1403
Abstract:
Maternal separation (MS) is defined as the termination of the continuity of mother-child relationship after the relationship is established. Although MS and maternal deprivation are different in terms of their definitions, these two terms are usually used interchangeably. This review aims to investigate the effect of MS on drug intake in adulthood. It has been proved that animal models are helpful in evaluating the effects of MS on drug intake risk in adulthood. There are relatively acceptable studies in this field on some drugs such as morphine, ethanol, and cocaine. However, very few animal studies, or even no animal study, have been conducted on some other drugs. The majority of these studies have considered MS as a risk factor for drug intake in adulthood. Different mechanisms are proposed for this phenomenon. Brain reward pathways are one of the main exploratory pathways of this process. Despite the importance of the issue, no human study with a specific concentration on investigating the relationship between MS and drug abuse in later life was found. Causal studies are warranted on humans to investigate the effect of MS on drug intake in later life.
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Authors
Fatemeh Delavari
PhD Candidate, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
Vahid Sheibani
Professor, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
Saeed Esmaeili-Mahani
Associate Professor, Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
Nouzar Nakhaee
Professor, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
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