Fabrication of Macro- AND Micropore Forming DCPD/ β-TCP Porous Scaffolds: Effect of Setting-Time Reaction and Acidic Calcium Phosphate Solution
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJMSEI-20-4_004
تاریخ نمایه سازی: 14 مرداد 1403
Abstract:
The coated β-tricalcium phosphate (β-TCP) with dicalcium phosphate dihydrate (DCPD) has attracted much attention in the biomaterials field due to the increase in its osteoconductivity. Besides, the porous bioceramic scaffolds with controlled pore sizes are significant in stimulating bone-like cell activity. In this study, the effect of the setting-time process and acidic-calcium phosphate (CaP) concentrations on the fabrication and properties of porous DCPD/ β-TCP scaffolds were studied. Subsequently, the specimens were examined using X-ray diffraction (XRD), scanning electron microscopy (SEM), compression strength and Fourier transforms infrared (FTIR). The study results revealed that the porous DCPD/ β-TCP scaffolds with macro- and micropore sizes were successfully obtained after the ۳۰۰-۶۰۰ µm of porous β-TCP granules were exposed to an acidic-CaP solution. Furthermore, the setting-time process and acidic-CaP concentrations increased the DCPD interlocking between granules, and the mechanical strengths of scaffolds increased up to ۰.۵ MPa. Meanwhile, the porosity levels were changed based on the formation of DCPD crystals. This study was expected to provide novel insights to researchers in the field of bioceramics through its investigation on the creation of porous DCPD/ β-TCP scaffolds.
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Authors
Ahmed Hafedh Mohammed Mohammed
School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, ۱۴۳۰۰, Nibong Tebal, Penang, Malaysia.Department of Materials Engineering, College of Engineering, Mustansiriyah University, Baghdad, Iraq.
Khairul Anuar bin Shariff
School of Materials and Mineral Resources Engineering, Engineering Campus, Universiti Sains Malaysia, ۱۴۳۰۰, Nibong Tebal, Penang, Malaysia.
Mohamad Hafizi Abu Bakar
Bioprocess Technology Division, School of Industrial Technology, Universiti Sains Malaysia, ۱۱۸۰۰, Gelugor, Penang, Malaysia.
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