A case of neuro-Behcet's disease complicated with intra-cardiac thrombosis

Intra-cardiac thrombus is an unusual and rare complication of  Behcet’s  (BD) with poor prognosis.  A ۳۲-year-old man with a history of mouth and genital ulcers since ۱۲ years ago was admitted to the neurology ward with complaints of headache and fever. Two years ago, the patient suffered from hydrocephalus due to cerebral vein thrombosis and a cerebral shunt was implanted for him. The patient was diagnosed with BD and was treated with glucocorticoids and cytotoxic drugs. During current hospitalization, with the diagnosis of shunt infection, the patient was treated with broad-spectrum antibiotics and the shunt was removed. On the ۱۰th day of hospitalization, he developed cough and palpitation without dyspnea. Echocardiography showed a ۲.۵ × ۴.۷ mm mass in the right ventricle, tricuspid regurgitation and pulmonary arterial pressure of ۳۲ mmHg. On computed tomography of the chest, the lung parenchyma was normal, but extension of the thrombus into the main pulmonary artery was reported.

Keywords:

Behcet’s disease , Behcet’s syndrome , intracardiac thrombosis , Pulmonary Hypertension , Surgery