Hypoglycaemia and Antioxidants Potential of Sorghum Bicolor Seeds

One of the most significant seeds crops in the world, Sorghum bicolor, is recognized for its vibrant phytochemicals, which may have medicinal uses. The aim of this study is to determine the antioxidant and hypoglycemic properties of Sorghum bicolor seeds. The ethanol and methanol extracts of these plants were subjected to antidiabetic conditioning using methods such as glucose adsorption capacity, muscle glucose uptake, and yeast glucose uptake, while iron-sulphate and sodium nitroprusside-induced lipid peroxidation were used to analyse the antioxidant capabilities. The results demonstrate that Sorghum bicolor's ethanol and methanol extracts adsorbed glucose, with the concentration of glucose adsorption rising as extract concentrations did. The muscle glucose uptake levels and glucose adsorption capabilities differed significantly (p ≤۰.۰۵). The yeast cells' ability to absorb glucose was likewise enhanced by the plant extracts, and glucose uptake was measured. In the brain and liver of iron-sulfurate-induced lipid peroxidation, the MDA (malondialdehyde) product was considerably (p ≤۰.۰۵) elevated. However, there was no significant change in the MDA product of sodium nitroprusside-induced lipid peroxidation. The ethanol and methanol extracts of Sorghum bicolor were found to have further potential as antioxidant and anti-glycemic agents, respectively, in this study.

Keywords:

Sorghum bicolor , Antioxidant , Hypoglycemic , Lipid peroxidation