Inadequate Control of Diabetes and Metabolic Indices among Diabetic Patients: A Population Based Study from the Kerman Coronary Artery Disease Risk Study (KERCADRS)

Background The goal of diabetes control should be feasible in order to minimize the risk of its adverse events and to reduce its burden and cost on patients. The current study aimed to assess the status of glycemic control in male and female patients with Type ۲ Diabetes Mellitus (T۲DM) in Kerman, Iran.   Methods In the present study, ۵۰۰ T۲DM (۳۰۰ women and ۲۰۰ men) from the Kerman Coronary Artery Disease Risk Study (KERCADRS), a population-based study from ۲۰۰۹ to ۲۰۱۱, were selected. Patients were >۱۸ years old, had Fasting Blood Sugar (FBS) higher than ۱۲۶ mg/dl, and had been through treatment for their diagnosed disease. All participants underwent Glycosylated Hemoglobin (HbA۱c) analysis. HbA۱c less than ۷% was considered as good glucose control. Other metabolic indices based on American Diabetes Association (ADA) target recommendations were considered.   Results The mean level of HbA۱c in total subjects was ۸.۵۶ ± ۴.۷۲% that only ۳۱.۶۶% of men and ۲۶.۰۰% of women had controlled level of HbA۱c. Total cholesterol less than ۲۰۰ mg/dl was reported in ۶۴.۵۰% of men and ۴۴.۰۰% of women, High Density Lipoprotein (HDL) more than ۴۰ mg/dl was revealed in ۲۰.۵۰% of men and ۳۴.۶۷% of women, and Low Density Lipoprotein (LDL) less than ۱۰۰ mg/dl was reported in ۴۱.۵۰% of men and ۲۵.۳۳% of women. In multivariate logistic regression model, longer duration of disease and higher Waist Circumference (WC) were positively associated with uncontrolled diabetes status.   Conclusion The findings of the present study revealed that diabetes control in T۲DM was inadequate. Changing the policy of treatment in individual patient and establishing better diabetes clinic to decrease the frequency of uncontrolled T۲DM are crucial. Paying attention to other affecting metabolic components such as WC in the process of T۲DM management is important.

Keywords:

Type ۲ Diabetes Mellitus (T۲DM) , Diabetes Control , Glycosylated Hemoglobin (HbA۱c) , Diabetes Care , Central Obesity