Comparison of the efficacy of lotrafilcon B and comfilcon A silicone hydrogel bandage contact lenses after transepithelial photorefractive keratectomy

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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JR_MEOP-10-2_001

تاریخ نمایه سازی: 16 مرداد 1403

Abstract:

Abstract Background: At completion of transepithelial photorefractive keratectomy (t-PRK) surgery, the eye is usually fitted with a bandage contact lens to reduce discomfort and promote epithelial healing. This study aimed to compare the outcomes of eyes fitted with lotrafilcon B versus comfilcon A, silicone hydrogel bandage contact lenses after t-PRK for the correction of low to moderate myopia, with or without astigmatism. Methods: In this comparative, prospective study, patients with myopia < -۶ D with or without astigmatism (< ۱.۷۵ D), who underwent t-PRK between January and June ۲۰۱۸, were randomly allocated to the lotrafilcon B and comfilcon A groups. Preoperative characteristics, including age, sex, eye treated, uncorrected visual acuity (UCVA), best-corrected visual acuity, mesopic pupil size, central corneal thickness, and refractive error were recorded. Postoperatively, pain score, UCVA, and corneal epithelial defect size on days ۱, ۴, and ۷ were compared between the two groups. Results: Twenty-nine eyes were included in each group. Demographic characteristics and preoperative measurements were similar between the two groups. UCVA was significantly improved on day ۷ as compared to day ۱ in the comfilcon A group (P = ۰.۰۳), but remained the same in the lotrafilcon B group (P = ۰.۷۰) as on day ۱ postoperatively. There was no significant difference in UCVA between the two groups at any follow-up visits (all P > ۰.۰۵). The pain score on the first postoperative day was significantly higher in the lotrafilcon B-fitted eyes than in the comfilcon A group (P < ۰.۰۰۱), but was significantly reduced in both groups compared to day ۱ (both P < ۰.۰۰۱). The epithelial defect in the comfilcon A group was significantly greater than in the lotrafilcon B group (P < ۰.۰۰۱) at day ۱ postoperatively, with significant improvement in both groups (both P < ۰.۰۰۱). Conclusions: Healing responses were better with lotrafilcon B than with comfilcon A bandage contact lenses. The patients had a greater mean pain score with lotrafilcon B than with comfilcon A lenses on the first postoperative day, yet the final outcome was comparable between the two groups. We did not encounter any postoperative complications related to contact lens wear.