Evaluating the quality of life in patients with ulcerative oral lesions

BACKGROUND AND AIM: Oral mucosal lesions can affect patient’s quality of life (QOL). In this evaluation, Persian version of Chronic Oral Mucosal Disease Questionnaire (COMDQ) was used to assess participants’ QOL. METHODS: This cross-sectional study was done during ۲۰۱۵-۲۰۱۶ in School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. ۹۵ participants with pemphigus vulgaris (PV), oral recurrent aphthous stomatitis (RAS), and oral lichen planus (OLP) enrolled is this study. The Persian version of COMDQ with ۲۶ questions and ۴ domains was used for assessing QOL. The data were analyzed in SPSS software. P-value less than ۰.۰۵ was considered significant. Independent t-test, analysis of variance (ANOVA), andTukey's test were used to assess scores of QOL. RESULTS: The final QOL scores were ۴۵.۹۵ ± ۱۶.۳۱, ۵۳.۳۸ ± ۱۷.۶۴, and ۵۰.۰۲ ± ۱۷.۳۶ for men, women, and all patients, respectively. Patients with OLP and RAS had good QOL, but patients with PV reported lower level of QOL (moderate). None of the COMDQ domains showed significant correlation with gender except pain and functional limitation and overall QOL score. CONCLUSION: The result of this evaluation revealed a good QOL; considering the type of oral disease, QOL ranged between moderate for patients with PV and good for patients with OLP and RAS.

Keywords:

Lichen Planus , stomatitis , Aphthous , pemphigus , Quality of Life