Dosimetric Characterization of ۳D Printed Bolus with Polylactic Acid (PLA) in Breast Cancer External Beam Radiotherapy

Introduction: In this study, ۳-Dimention (۳D) polylactic acid (PLA) bolus were characterized as human tissue equivalent and specially designed for use in electron radiotherapy of breast cancer. Material and Methods: This study uses the main material PLA with variations in the infill percentage when printing, which is  (۲۰, ۴۰, ۶۰, ۸۰, and ۱۰۰) %. Dosimetric characterization included measuring the value of Relative Electron Density (RED) and measuring the absorbed dose using LINAC ۱۵ MeV, which was tested using a breast mannequin and compared with a commercial bolus at Andalas University Hospital. Results: The results showed that the ۳D bolus made of PLA provided uniformity in terms of thickness so that every part of the body surface covered by the bolus would get an even dose. ۳D bolus made of PLA in all variations in the infill percentage had a RED value equivalent to human tissue. They can help ensure that the bolus does not significantly change the radiation dose distribution, achieving optimal treatment outcomes. However, a bolus with an infill percentage of ۲۰% has a RED value closest to the breast RED, which is ۰.۹۹ and can absorb radiation of ۱.۹۸ Gy more optimally compared to a commercial bolus that can absorb ۱.۹۷ Gy from ۲ Gy doses given. Conclusion: The ۳D bolus made of PLA can be an effective alternative for treating breast cancer using electron radiotherapy.

Keywords:

۳D Bolus , Absorbed Dose , infill percentage , Polylactic Acid , relative electron density