An overview of the positive effect of endophytic bacteria and medicinal plants on the production of bioactive compounds

Bioactive compounds from medicinal plant sources are of great interest to scientists due to their druggability and their health benefits for plants, animals, and humans. Besides that, bioactive compounds and pure phytochemicals have also been discovered in endophytic bacteria that are found in plant tissues. As a result of the symbiosis, plants also benefit greatly from harboring these endophytes, as these bacteria promote plant growth and improve the resistance of plants to various pathogens. Endophytes can induce both biotic and abiotic stress tolerance in inoculated plants. Moreover,bacterial endophytes increase the plants’ resistance against diseases, pests, and parasites, and are a promising source of pharmaceutically important bioactives. For instance, the production of antibiotics, auxins, biosurfactants, cytokinin’s, ethylene, enzymes, gibberellins, nitric oxide organic acids, osmolytes, and siderophores is accredited to the existence of various bacterial strains. Thus, this manuscript intends to review the sustainable applications of endophytic bacteria to promote the growth, development, and chemical integrity of medicinal and herbal plants. The study of the importance of bacterial endophytes in the suppression of diseases in medicinal and herbal plants is crucial and a promising area of future investigation

Keywords:

medicinal plants , microorganisms , endohytes , bacteria , secondary metabolites