Copper(II) Oxide-Catalyzed Synthesis of Dihydroquinazolinfrom Isocyanides and Guanidine Derivatives

simple and appropriate procedure for the synthesis of dihydroquinazolin derivatives via the Cu-catalyzedintramolecular C-H activation reaction from isocyanides and N, N′, N′′-trisubstituted guanidines, generatedby copper(II) oxide-catalyzed hydroamination of carbodiimides is reported.

Keywords:

Cu-catalyzed , Dihydroquinazolin , C-H Activation , Isocyanides , Guanidines