Synthesis and Characterization of Novel Nanomaterials for Drug Delivery Applications

Nano systems synthesized from organic and inorganic materials have attracted a lot of attention for biomedical applications. These applications can be in the fields of biosensors, manufacturing imaging systems, synthesis of drug carriers and targeted drug delivery. The use of particles for drug delivery was first popularized by using diagnostic drugs in reticuloendothelial systems (liver, spleen, bone marrow, and lymph nodes) and caused the increasing expansion of micro particle systems. Increasing the dissolution of drugs by reducing the particle size is one of the most important goals of using these particles. However, the use of micro particles has many other advantages. The results of the present study showed that by reducing the particle size of drugs, their shelf life in the body is increased. Because the particles are less accessible to the elimination systems of the body, such as kidney, liver, etc., and as a result, the possibility of removing them from the body decreases. For this reason, the shelf life of medicines in the body increases and the number of times the medicine is used decreases. Also, with this method, in addition to the lower cost that the patient pays due to reducing the frequency of drug use, the side effects of the drug also appear less in the patient. Consuming regimens lead to more patients. Over many years, the use of micro particles became very popular and was able to make valuable progress in the field of drug therapy, but micro-scale materials often show the same physical characteristics as bulk and macromolecules. In addition, the results showed that for more access to the cells and drug delivery to them, the drug carrier should be in the dimensions of the cells themselves and their internal organs.

Keywords:

Nano medicine , Patient , Injection method , synthesis of drug carriers , Micro particles