The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome

Introduction: Endothelial dysfunction is a consequence of obesity and metabolic syndrome. In this study, the effect of CX Works training (CX) on serum endothelial microparticles (EMPs) and nitric oxide (NO) as markers of vascular endothelial function was measured in women with metabolic syndrome. Methods: For this purpose, ۲۴ sedentary adult obese women were randomly divided into CX (۸ weeks, n= ۱۲) and control (no training, n = ۱۲) groups. CX were performed every other day for ۸ weeks. Serum NO and EMPs after an overnight fast were measured in both study groups (pre-training) and measurements were repeated ۴۸ hours after the last CX training session (post-training). Independent / paired t-test was used to compare between groups. Results: CX training resulted in significant increase in serum NO and decrease in EMPs compared to the pre-training (p<۰.۰۵). No significant change were observed in any variables in control groups (p>۰.۰۵). Conclusion: CX training, as a novel exercise modality, is associated with improved vascular endothelial function in women with metabolic syndrome. Measurement of other vascular markers is needed to better understand the mechanisms responsible for these changes.

Keywords:

CX training , Metabolic syndrome , Nitric Oxide , Endothelial microparticles