Release of tetracycline hydrochloride from (methacrylamide–comethacrylic acid)/ montmorillonite nanocomposite hydrogels
Publish place: 07th International Congress on Chemical Engineering
Publish Year: 1390
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICHEC07_465
تاریخ نمایه سازی: 25 فروردین 1394
Abstract:
Nanocomposites hydrogel composed of methacrylamide (MAAm), methacrylic acid (MAAc) and montmorillonite (cloisite 15A) were prepared and studied for swelling behavior and control drug release of tetracycline hydrochloride. X-ray diffraction analysis showed that the MMT incorporated into the nanohydrogel exhibited an exfoliated nanostructure. The exfoliated silica nanosheets are able to act as cross-linkers to form a network structure between the polymer andMMT, and this difference in the cross-linking density strongly affects the release of tetracycline. Results showed that the swelling ratio for the present nanocomposite hydrogels increased with an increase of montmorillonite. Finally, the pH-responsive behaviors of these hydrogels were investigated
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Authors
a Yeganeh
Department of Chemical Engineering, Faculty of Engineering, Arak University, Arak ۳۸۱۵۶-۸-۸۳۴۹, Iran
a barati
Department of Chemical Engineering, Faculty of Engineering, Arak University, Arak ۳۸۱۵۶-۸-۸۳۴۹, Iran
t miri
Department of Chemical Engineering, Faculty of Engineering, Arak University, Arak ۳۸۱۵۶-۸-۸۳۴۹, Iran
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