Isolation and structure elucidation of coumarin and cinamate derivatives from Lycium ruthenicum

Lycium species is a popular medicinal plant in the traditional Chinese medicine and Lycium ruthenicum is a native medicinal plant of Iran. Lycium genus has several biologically importantproperties too. Investigation of chemical composition of ethyl acetate extract of this plant is the goal of this study. Two coumarins (Scopoletin and Sculetin) and Methyl-2-hydroxy-4- undecanoxy-trans-cinamate were isolated and characterized as the major constituents using 1H NMR, 13C NMR and FT-IR spectroscopic data, MS spectrometry, elemental analysis and bycomparison with the literature values. Phytochemical investigation of Lycium ruthenicum demonstrated the presence of important biologically active compounds. This is the first phytochemicalstudy of this species in Iran.

Keywords:

Lycium ruthenicum , traditional medicine , phytochemistry , coumarine , Scopoletin , Esculetin