Heterogeneous SnCl2/Mesoporous Silica Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine Derivatives under Solvent-Free Conditions

A highly efficient and general method for the synthesis of 1,8-dioxodecahydroacridine is established through a one-pot multicomponent cyclocondensation of aromatic aldehyde and ammonium acetate with 2 equivalents dimedone using nanomesoporous silica supported SnCl2 as a catalyst. Mesoporous molecular sieves consist of an ordered array of silica tubules comprised of pores with uniform controllable diameters in the nanometer rang (2-10 nm). In this method SnCl2/mesoporous silica was used as green and reusable catalyst. Excellent yields, short reaction times, simple workup, and inexpensiveness and commercially availability of the catalyst are the advantages of this method.

Keywords:

Mesoporous silica , Heterogeneous catalyst , One-pot synthesis , 1 , 8- Dioxodecahydroacridines , Multicomponent reaction