An Eco-friendly Process for the One-pot Synthesis of 2-amino-3-cyano- 4H-pyrans in the Presence of Nano Ionic Liquid

In this study, tris(hydroxymethyl)methane ammonium hydrogensulphate [(THA)(HSO4)] was synthesized as the nano ionic liquid via a simple chemical route in water. The [(THA)(HSO4)] ionic liquid was characterized by various techniques such as XRD, SEM, TEM, 1H NMR, 13C NMR, FT-IR, MS andelemental analysis. [(THA)(HSO4)] ionic liquid was successfully applied as an eco-friendly and recyclable catalyst for the one-pot synthesis of 2-amino-3-cyano-4H-pyran derivatives through three-component reaction aldehyde, malononitrile and dimedone. Taking the environment and economy into consideration, the work presented here has the merits of environmental friendliness, high yields, simple work-up, easy operation and the avoidance of the organic solvents and inexpensive catalysts.

Keywords:

Ionic liquid , 2-Amino-3-cyano-4H-pyran , Three-component reaction , Reusable , Nano