Evaluation of the relationship between maternal lifestyle and adipokine profiles in mother and neonate

Background: Past studies showed that mother’s lifestyle during pregnancy have influenced neonatal outcomes, but the exact mechanism of this effect is unclear. Given that there has not been enough research about this relationship so far, our aim is to evaluate the relationship between maternal lifestyle and maternal and neonatal adipokine profiles in a review. Methods: 15 articles were obtained with searching PubMed, Springer, Elsevier, Scopus and Google Scholar databases, of which 7 articles were reviewed.Results: The findings show that weight gaining during pregnancy and its speed affect the serum levels of glucose and adipokine in the neonates, and overweight during pregnancy can have a metabolic effect on both mother and neonate, but studies on the relationship between maternal lifestyle and maternal and neonatal adipokine levels are very limited.Conclusions: The results of the review show that higher adipokine levels in mothers are associated with an increase in fat mass in newborns, and there is a significant relationship between maternal adiponectin deficiency and neonate’s weight loss at birth. The maternal adipokine profile also correlates maternal nutritional status and lipid metabolism to fetal-placental function. Transferring of the nutrients to the fetus is regulated through the complex interaction of insulin signaling, cytokine function and insulin response modulated by adipokines. Finally, maternal metabolic status and lifestyle can have an important effect on the neonate adipokine profile regulating

Keywords:

Adipokine profile , Maternal Life Style , Adiponectin , Neonate , Adipose Tissue