Background Children are more likely to be burned than other age. The aim of this study was to determine the burn-related factors in children in Kermanshah province, Iran. Materials and Methods In the present hospital based case-control study, 198 under 15 years age children who were burned ( from beginning of spring 2016 until the end of spring 2017), enrolled into the study as cases and 198 children referred to the hospital for non-burning reasons selected as controls. The cases and controls were frequency matched for age and gender variables. Principal Component Analysis test was used to construct the socioeconomic variable and univariate, moreover multivariate logistic regression tests were used to determine the burn-related factors. All analyses were carried out using SPSS software version 21.0. Results: The mean age of children with burns was 4.3 ± 3.5 years. The most common factor of burns was hot liquids with 48.5%. Body mass index (Odds Ratio (OR)=1.252, P= 0.004), number of household members more than 5 body (OR=8.472, P<0.001), absence of more than one watchful (OR=2.481, P=0.026), hours without watchful (OR=8.649, P<0.001), illiterate mother (OR=9.778, P=0.002), petroleum storage at home (OR=1.815, P=0.046), and the lowest quartile of socioeconomic level (OR=7.220, P<0.001) increased the chance of burning in children. Increase of mother age (OR=0.938, P=0.005) and the worker father (OR=0.233, P=0.002) reduced this chance. Conclusion: Based on results of current study, burning in children is a multifactorial outcome including individual, social and environmental factors such as Body mass index, household size, mother age, father job, less watchful, hours without watchful, illiterate mother, petroleum storage at home, and socioeconomic status.