Metachronous Malignant Fibrous Histiocytoma- A Rare Case Report
Publish place: IRANIAN JOURNAL of PATHOLOGY، Vol: 13، Issue: 4
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJP-13-4_014
تاریخ نمایه سازی: 23 تیر 1398
Abstract:
Malignant fibrous histiocytoma (MFH) is one of the most common types of soft tissue sarcomas in adults. Distant metastases are developed in 30–40% of patients with MFH, with the most common site being the lung. However, metachronous MFH has not been reported previously in literature. This report describes a case of a 30-year-old man, who had two metachronous thigh tumors, both of which were confirmed to be MFH on histopathology and immunohistochemistry evaluations. A contemporary multidisciplinary approach to therapy including surgery, radiation and chemotherapy was advocated. Two primary sites of MFH raised the possibility of a genetic abnormality that could predispose such a patient to develop multiple primary sites of the same tumor.
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Authors
Gireesha Rawal
Dept. of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India
Sufian Zaheer
Dept. of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India
Amit Yadav
Dept. of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India
Indrani Dhawan
Dept. of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India