Synthesize and Functionalize of the Novel Choline Chloride/2- Chloroacetylchloride/PEI Derivatives for Applications inEnzyme Stabilization
Publish place: 26th Iranian Seminar on Organic Chemistry
Publish Year: 1397
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ISOC26_192
تاریخ نمایه سازی: 2 شهریور 1398
Abstract:
Deep eutectic solvents (DESs) are new generation of solvents [1] which defined as a mixtureof two or more components. DES may be solid or liquid which show a high melting point depressionbecoming liquids at room temperature. The DESs are so called natural deep eutecticsolvents when constitute based on aminoacids, organic acids, sugars, or choline derivatives[2].Herein, we present a novel DES based on functionalized polyethylene imine as hydrogenbond donor and choline chloride (Fig. 1). The application of the novel DES was investigatedon the uricase stabilization and immobilization. The synthesized DES was shown high abilityto the enzyme immobilization with interesting increase in the uricase activity up to 4 times.
Authors
Maryam Khorsandi
Department of chemistry, Graduate University of Advanced Technology, Kerman, Iran
Elaheh Mosaddegh
Department of New Materials, Institute of Science and High Technology and Environmental Sciences, GraduateUniversity of Advanced Technology, PO Box ۷۶۳۱۵-۱۱۷, Kerman, Iran
Masoud Torkzadeh-Mahani
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Saba Ghanbari
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran