A Novel Experience in Treatment of Liver Hydatidosis in Pediatrics: A Clinical Trial Study
Publish place: International Journal of Pediatrics، Vol: 5، Issue: 10
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_INJPM-5-10_017
تاریخ نمایه سازی: 20 مهر 1398
Abstract:
Background Hydatidosis is a conventional health public problem in most parts of the world. Safe treatment of patients with hydatidosis has been a topic of debate for a long time. Surgical treatment always was associated with high morbidity and mortality. Medical treatment is also controversial. In this study, alternative procedure named Percutaneous, Aspiration and hypertonic Saline Instillation (PAHSI) was applied to treat patients with hydatidosis. Materials and Methods In this single-blind clinical trial, thirty-eight patients, ranging in age between 6 months and 16 years, with 81 hepatic hydatid cysts underwent PAHSI treatment. The consecutive steps including sonographic guidance, aspiration of cyst content and injection of 15% saline hypertonic were carried out in this method. Patients with multiple cysts also were treated by this procedure. Results Participants were 18 boys (47.3%) and 20 girls (52.6%) with mean age of 8.08+ 3.92 years. Almost half of the patients had single cyst (52.63%). During 2- year follow- up, no recurrences were observed; therefore, re-hospitalization and possible complications reduced considerably. Furthermore, this method was applicable to cure multiple cysts. Conclusion In PAHSI strategy, it seems that the complications of surgery (laparotomy and anesthesia) decreased since no complications observed after procedure, and cosmetic results in future are much better due to avoidance of incision.
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Authors
Marjan Joodi
Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali Alamdaran
Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Elham Bazrafshan
Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Morteza Peyvandi
Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.