Correlation Between Blood Lactate Level and Hospitalization and Prognosis in Drug Intoxication Patients in Emergency Medicine Department

Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
View: 272

This Paper With 5 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

این Paper در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_PJMT-8-2_002

تاریخ نمایه سازی: 23 مهر 1398

Abstract:

Background: Several drug intoxications can affect both pulmonary and cellular respiration. We therefore think that assessing blood lactate levels can provide information about prognosis. Blood lactate levels have provided information about prognosis in several diseases involving hypoxia at the cellular level, such as sepsis and trauma. The purpose of this study was to determine whether there is any relation between blood lactate levels and mortality, morbidity, and prognosis in patients presenting to the emergency department with drug intoxication. Methods: This retrospective cross-sectional study involved patients admitted to the emergency department due to suicidal drug intoxication over a one-year period (January to December 2016). The primary outcome measure was the relationship between serum lactate concentrations and patient discharge or hospitalization, and if hospitalized, the duration of stay. The secondary outcome measure was the relationship between serum lactate concentrations and toxic dose intake in single-drug intoxication. Results: We enrolled 372 patients, of whom 192 were analyzed after exclusion criteria application. The mean blood lactate level in the total patient group was 2.6±1.46, and 2.7±1.9 in the single drug group and 2.5±1.3 in the multidrug group. Also, blood lactate levels in the overdose group and toxic dose group were 3.4±3.0 and 2.4±0.9, respectively. No significant differences were determined in the lactate level, discharge, hospitalization and the length of hospital stay between the single drug and multidrug groups. In the toxic dose group, patient ages and number of admissions to intensive care unit were significantly higher than in the overdose group. The number of discharges was significantly lower in the toxic dose group. No correlation was determined between the serum lactate level and the length of hospital stay. Conclusion: Lactate level is not a useful parameter for predicting hospitalization in drug intoxication patients.

Authors

Adnan Turk

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey

Asım Kalkan

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey

Şeref Emre ATİŞ

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey

Mehmet Ali Topal

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Wax PM. History. In: Toxicologic Emergencies. eds. Goldfrank LR, Flomenbaum ...
  • Mégarbane B. Toxidrome-based approach to common poisonings. Asia Pac J ...
  • Akköse Ş, Fedakar R, Bulut M, Çebicci H, Zehirlenme Olgularının ...
  • Manini AF, Stimmel B, Hoffman RS, Vlahov D. Utility of ...
  • Cheung R, Hoffman RS, Vlahov D, Manini AF. Prognostic Utility ...
  • Fall PJ, Szerlip HM. Lactic acidosis: from sour milk to ...
  • Mankis P, Jankowski S, Zhang H, Kahn RJ, Vincent JL. ...
  • Thomsen MT, Lefevre S, Nilsson GE, Wang T, Bayley M. ...
  • Prasad M, Murthy DR, Kumar S, Malini SS. Effects of ...
  • Shojaeepour S, Mandegary A, Fazeli M, Sayed-Mirzaei SM, Ahmadi N, ...
  • O’Donovan FC, Owens J, Tracey JA. Self-poisoning: admission to intensive ...
  • Burillo-Putze G, Munne P, Dueñas A, Pinillos MA, Naveiro JM, ...
  • Shapiro NI, Howell MD, Talmor D, Nathanson LA, Lisbon A, ...
  • Callaway DW, Shapiro NI, Donnino MW, Baker C, Rosen CL. ...
  • Smith I, Kumar P, Molloy S, Rhodes A, Newman PJ, ...
  • Serinken M, Yanturalı S. Acil serviste intihar amaçlı zehirlenmelerin geriye ...
  • Buchanan WJ. A year of intentional self-poisoning in Christchurch. N ...
  • Lionte C, Sorodoc V, Tuchilus C, Cimpoiesu D, Jaba E. ...
  • Flomenbaum NE, Goldfrank LR, Kulberg AG, et al. General management ...
  • Bertolote JM, Fleischmann A. A global perspective in the epidemiology ...
  • WHO. Global Health Estimates Disease burden and mortality estimates [Internet]. ...
  • Cervellin G, Comelli I, Rastelli G, Picanza A, Lippi G. ...
  • Megarbane B, Deye N, Malissin I, Baud FJ. Usefulness of ...
  • نمایش کامل مراجع