The first report of the blaNDM carbapenemase genes in Salmonella spp. isolates in Kerman, Iran
Publish place: 20th International Congress of Microbiology of Iran
Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
MEDISM20_052
تاریخ نمایه سازی: 26 بهمن 1398
Abstract:
Introduction and Objectives: spreading of multidrug resistant (MDR) strains of Salmonella spp. is an important global health issue. In fact, these MDR strains of Salmonella spp. act as a reservoir and subsequent horizontal spreading of antibiotic resistance genes to non-resistant ones. In this study, we aimed to identify the antimicrobial resistance genes (blaSHV, blaTEM, blaCTX-M and blaNDM) in Salmonella spp., isolated from chicken feces by PCR method. sMaterials and Methods: In this study, a total of 45 Salmonella spp. isolates were collected from chicken feces samples. The isolates confirmed as Salmonella spp. by standard biochemical tests and presence of antimicrobial resistance genes including blaSHV, blaTEM, blaCTX-M and blaNDM determined by PCR methods. Results: The results revealed that 16 (35.5%), 6 (13.4%) and 1 (2.3%) of Salmonella spp., carried blaTEM, blaNDM and blaCTX-M genes, respectively, while blaSHV gene was not detected. Conclusion: The blaTEM, blaNDM and blaCTX-M genes are common among the Acinetobacter spp., Escherichia coli and Klebsiella spp and numerous isolates from human patients, and some environmental niches such as water and sewage and also recently have been isolated from farm (livestock) animals in China. Based on our results presence of blaTEM, blaNDM and blaCTX-M genes in investigated isolates indicates a serious alarm for the prevalence of these genes and subsequent spread from animals to people. We recommended that the use of antibiotics in chicken food must be tightly regulated to avoid such outcomes.
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Authors
Davood Kalantar-Neyestanaki
Department of Microbiology and Virology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Reza Ghanbarpour
Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
Sajad Aslani
Department of Microbiology and Virology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Sanaz Dehdashti
Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.