Clinical outcome of frozen thawed embryo transfer in three different cycle regimens

Background and Aim : Many studies have been carried out to understand the effect of endometrialthickness on the reproductive outcome while the factors affecting the pattern itself are still unknown.Methods : This study was conducted as a single blind randomized clinical trial study on 180 infertilewomen considered for IVF. Endometrial thickness measurement was done in each group (natural, letrozle,and agonist, 60 patients in each group). Correlation between endometrial thickness and factors such asclinical pregnancy, FHR, βHCG and pregnancy rate were assessed. Data analyses, including parametricand nonparametric tests were undertaken using the SPSS 16 software. A P value < 0.05 was regarded asstatistically significantResults : The mean endometrial thickness was 8.46±1.35 mm. and 8.13±1.15, 7.99±1.06, and 8.89±1.35in natural, Letrozole, and agonist group respectively, there was a significant difference among groups(P<0.001). There were no significant differences among groups in βHCG, FHR, median transfer fetus andclinical pregnancy (P> 0.05).Conclusion : We did not find any correlation between endometrial preparation methods and FHR, βHCG,and clinical pregnancy.

Keywords:

endometrial thickness , IVF , Letrozole , Freeze Emryo Transfer