Gross hematuria and AKI in woman with IgA nephropathy

مقدمه: Gross hematuria is one of the common symptoms in IgA nephropathy. Transient AKI with gross hematuria was reported in some literature but it may due to severe and crescentic IgA nephropathy• معرفی بیمار: Patient is 60 year old female who comes with chief complaint of hematuria since one week ago she is known case of biopsy proven IgA nephropathy from years ago. Her serum creatinine rise from 1.5 mg/dl to 3.9mg/dl. She was admitted at hospital and received some hydration, underwent ultrasonography and lab exams. There were no significant abnormality except 2000 mg/d proteinuria. Serologic tests was almost normal. Her serum creatinine raised up to more than mg/dl. She received methyl prednisolone pulse for days and then she put on 1mg/Kg prednisolone and 1.5 mg/Kg cyclophosphamide. She underwent renal biopsy. The result of biopsy was active IgA nephropathy with crescent formation in some glomeruli. Her proteinuria and serum creatinine improved gradually. Cyclophophamide was discontinued after one month because of severe leukopenia. Prednisolone was tapered gradually and stopped after months.. بحث نتیجه گیری:Patients with Iga nephropathy may be asymptomatic, with persistent microscopic hematuria and proteinuria and hypertension. For this cases first we take kidney biopsy to confirm the diagnosisthen start drug thrapy

Keywords:

AKI , IgA nephropathy , hematuria