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title

Biocompatibility evaluation of bioglass nanoparticles to chondrocyte cells by isothermal microcalorimetry

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Year: 2010
Present: شفاهي
COI code: ICBME17_219
Paper Language: English

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Authors Biocompatibility evaluation of bioglass nanoparticles to chondrocyte cells by isothermal microcalorimetry

  Ali Doostmohammadi - Biomaterials Group, Materials Engineering Department Isfahan University of Technology (IUT) Isfahan, Iran
  Ahmad Monshi - Biomaterials Group, Materials Engineering Department Isfahan University of Technology (IUT) Isfahan, Iran
  Rasoul Salehi - Department of Genetics and Molecular Biology, School of Medicine Isfahan University of Medical ScienceIsfahan, Iran
  Saeid Karbasi - Biomedical Engineering Department, School of Medicine Isfahan University of Medical ScienceIsfahan, Iran

Abstract:

This study aimed at the biocompatibility evaluation of bioglass nanoparticles to chondrocyte cells using isothermal micro/nano calorimetry (IMNC), which is a new method to study cell/biomaterial interactions. For this purpose, 63S bioglass nanoparticles were made via sol-gel method and primary characterization was carried out on the particles. XRD analysis showed the amorphous structure of the glass and the particle size and morphology were investigated by SEM. Finally the bioglass nanoparticles’ biocompatibility with yeast and cultured humanchondrocyte cells was evaluated using IMNC. The results showed no deleterious effect on chondrocyte growth and they can grow, proliferate and live on beside bioglass nanoparticles. In another word, the obtained results from this study confirmed the growth, proliferation and viability of chondrocyte cells close to 63S bioactive glass nanoparticles at low concentrations.

Keywords:

biocompatibility; bioglass; chondrocyte cells;microcalorimetry

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COI code: ICBME17_219

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Doostmohammadi, Ali; Ahmad Monshi; Rasoul Salehi & Saeid Karbasi, 2010, Biocompatibility evaluation of bioglass nanoparticles to chondrocyte cells by isothermal microcalorimetry, 17th Iranian conference on Biomedical Engineering, اصفهان, انجمن مهندسي پزشكي ايران, دانشگاه علوم پزشكي اصفهان, https://www.civilica.com/Paper-ICBME17-ICBME17_219.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Doostmohammadi, Ali; Ahmad Monshi; Rasoul Salehi & Saeid Karbasi, 2010)
Second and more: (Doostmohammadi; Monshi; Salehi & Karbasi, 2010)
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Type: state university
Paper No.: 13220
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