Saccharin as a new organocatalyzed: a fast, highly efficient and environmentally friendly protocol for synthesis of imidazo[1,2-α]pyridine derivatives via a one-three component reaction

In this research article, we report the synthesis of imidazo[1,2-a]pyridine derivatives through Ugi condensation in the presence of saccharin as an organocatalyst used in a three component reaction. The convenient synthetic protocol, short reaction times, easy work up, good to excellent yields and mild reaction conditions make this process both practical and attractive.

Keywords:

Three-component reaction Ugi condensation Saccharin Imidazo[1 , 2-α]pyridine